In a large mixing bowl, combine the ground beef, breadcrumbs, eggs, minced garlic, freshly grated Parmesan cheese, milk, chopped parsley, dried oregano, salt, and pepper. Mix gently until just combined.

Transfer the mixture into a parchment-lined loaf pan or shape it on a baking sheet to form a compact loaf shape.

Preheat your oven to 375°F (190°C). Bake the loaf for 45–55 minutes until the internal temperature reaches 160°F (71°C).

Brush the top with garlic butter or marinara sauce during the last 10 minutes of baking for an extra layer of flavor.

Let the meatloaf rest for 10 minutes on a cutting board before slicing.